BDBM38234 US10201527, Compound 49::US10736881, Compound 49::US8551988, 39

SMILES Cn1cnc2cc(\C=C\C(=O)NO)ccc12

InChI Key InChIKey=FDOMGLWLNARRRF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 38234   

TargetHistone deacetylase 8(Human)
Mei Pharma

US Patent
LigandPNGBDBM38234(US8551988, 39 | US10201527, Compound 49 | US107368...)
Affinity DataIC50: 201nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM38234(US8551988, 39 | US10201527, Compound 49 | US107368...)
Affinity DataIC50: 1.22E+3nMAssay Description:The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM38234(US8551988, 39 | US10201527, Compound 49 | US107368...)
Affinity DataIC50: 1.40E+3nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM38234(US8551988, 39 | US10201527, Compound 49 | US107368...)
Affinity DataIC50: 1.40E+3nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent