BDBM383507 US10280149, Example 12::[(3R)-1-cyclobutyl-3-piperidyl]-(2,4-dimethoxyphenyl)methanone

SMILES COc1ccc(C(=O)[C@@H]2CCCN(C2)C2CCC2)c(OC)c1

InChI Key InChIKey=MKNOOJFMMRTJJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383507   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383507BDBM383507([(3R)-1-cyclobutyl-3-piperidyl]-(2,4-dimethoxyphen...)
Affinity DataIC50: 9.00E+3nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
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Date in BDB:
2/21/2020
Entry Details
US Patent