BDBM383518 US10280149, Example 27::[1-(cyclopropylmethyl)-3-piperidyl]-[3-(4-fluorophenoxy)phenyl]methanone

SMILES Fc1ccc(Oc2cccc(c2)C(=O)C2CCCN(CC3CC3)C2)cc1

InChI Key InChIKey=RYJFCIWDGHWSHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383518   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383518BDBM383518([1-(cyclopropylmethyl)-3-piperidyl]-[3-(4-fluoroph...)
Affinity DataIC50: 221nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent