BDBM383526 US10280149, Example 35::[1-(cyclopropylmethyl)-3-piperidyl]-[4-(hydroxymethyl)-2-naphthyl]methanone

SMILES OCc1cc(cc2ccccc12)C(=O)C1CCCN(CC2CC2)C1

InChI Key InChIKey=VJSSHBAHEAMDPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383526   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383526BDBM383526([1-(cyclopropylmethyl)-3-piperidyl]-[4-(hydroxymet...)
Affinity DataIC50: 169nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
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Date in BDB:
2/21/2020
Entry Details
US Patent