BDBM383528 US10280149, Example 37::[4-(aminomethyl)-2-naphthyl]-[1-(cyclopropylmethyl)-3-piperidyl]methanone

SMILES NCc1cc(cc2ccccc12)C(=O)C1CCCN(CC2CC2)C1

InChI Key InChIKey=GOCMJUSXIMRCNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383528   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383528BDBM383528([4-(aminomethyl)-2-naphthyl]-[1-(cyclopropylmethyl...)
Affinity DataIC50: 620nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent