BDBM383623 (1-(cyclopropylmethyl)-4-methylpiperidin-3-yl)(5-methoxynaphthalen-2-yl)methanone::US10280149, Example 136b

SMILES COc1cccc2cc(ccc12)C(=O)[C@@H]1CN(CC2CC2)CC[C@@H]1C

InChI Key InChIKey=ANLDPHOWYDOFHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383623   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383623BDBM383623((1-(cyclopropylmethyl)-4-methylpiperidin-3-yl)(5-m...)
Affinity DataIC50: 1.20E+3nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent