BDBM383651 (1-cyclobutylpiperidin-3-yl)(2-(methylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)methanone::US10280149, Example 149

SMILES CS(=O)(=O)N1CCc2cc(ccc2C1)C(=O)C1CCCN(C1)C1CCC1

InChI Key InChIKey=JLVWWDRLJFGPBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383651   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383651BDBM383651((1-cyclobutylpiperidin-3-yl)(2-(methylsulfonyl)-1,...)
Affinity DataIC50: 163nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent