BDBM383666 6-(1-(cyclopropylmethyl)-4-methylpiperidine-3-carbonyl)-2-naphthonitrile::US10280149, Example 160b

SMILES C[C@@H]1CCN(CC2CC2)C[C@H]1C(=O)c1ccc2cc(ccc2c1)C#N

InChI Key InChIKey=IFJBMGJQTLRTMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383666   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383666BDBM383666(6-(1-(cyclopropylmethyl)-4-methylpiperidine-3-carb...)
Affinity DataIC50: 113nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent