BDBM383959 US10280166, Compound 25

SMILES Fc1cccc(c1)-c1ccnc2[nH]c(nc12)-c1n[nH]c2ccc(cc12)-c1cncc(CN2CCC(F)(F)C2)c1

InChI Key InChIKey=GKNSBZOTFOXLBF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383959   

TargetProto-oncogene Wnt-1(Human)
Samumed

US Patent
LigandPNGBDBM383959(US10280166, Compound 25)
Affinity DataIC50: 1nMAssay Description:Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent