BDBM384037 US10280166, Compound 421

SMILES Cc1ccncc1-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3cc(F)cc(CNS(C)(=O)=O)c3)c2c1

InChI Key InChIKey=LMAACPJBHOJDGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384037   

TargetProto-oncogene Wnt-1(Human)
Samumed

US Patent
LigandPNGBDBM384037(US10280166, Compound 421)
Affinity DataIC50: 6.10nMAssay Description:Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2020
Entry Details
US Patent