BDBM385076 BDBM445984::US10287258, Example 36::US11667615, Example 36::US11680049, Example 36::US20230278969, Example 36

SMILES CC[C@H](NC(=O)[C@@H]1CNCCCO1)\C=C\C(=O)N1CCc2ccccc12

InChI Key InChIKey=OHNHQTNQBQMALV-LFGVRAQPSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 385076   

TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:Examples 36-37: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of amino methyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM385076(BDBM445984 | US10287258, Example 36 | US11667615, ...)
Affinity DataIC50:  5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent