BDBM387088 (2-(2H-1,2,3-triazol-2-yl)phenyl)((3aR, 7aR)-1- (4,6-dimethylpyrimidin-2-yl)hyexahydro-1H- pyrrolo[2,3-c]pyridin-6(2H)-yl)methanone::US9938276, A2

SMILES Cc1cc(C)nc(n1)N1CC[C@@H]2CCN(C[C@H]12)C(=O)c1ccccc1-n1nccn1

InChI Key InChIKey=GAJNOIONAPXARW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387088   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387088((2-(2H-1,2,3-triazol-2-yl)phenyl)((3aR, 7aR)-1- (4...)
Affinity DataIC50: 163nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM387088((2-(2H-1,2,3-triazol-2-yl)phenyl)((3aR, 7aR)-1- (4...)
Affinity DataIC50: 1.00E+4nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details
US Patent