BDBM387486 N3-(3-Ethynyl- 4- fluorophenyl)- 7-(pyridin-4- yl)furo[2,3- c]pyridine-2,3- diamine::US10294212, No. 111

SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(c1)C#C)-c1ccncc1

InChI Key InChIKey=AVPNERFXBKZEPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 387486   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Curadev Pharma

US Patent
LigandPNGBDBM387486(US10294212, No. 111 | N3-(3-Ethynyl- 4- fluorophen...)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent