BDBM387561 N3-(3- Chloro-4- fluorophenyl)- 7-(2- morpholino- pyridin-4- yl)furo[2,3- c]pyridine-2,3- diamine::US10294212, No. 154

SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1ccnc(c1)N1CCOCC1

InChI Key InChIKey=ARHQGLADNSROFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 387561   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Curadev Pharma

US Patent
LigandPNGBDBM387561(US10294212, No. 154 | N3-(3- Chloro-4- fluoropheny...)
Affinity DataIC50: 200nMAssay Description:Human indoleamine 2,3-dioxygenasel (hIDO1) catalyzes the oxidative cleavage of the pyrrole ring of the indole nucleus of tryptophan to yield N-formyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Curadev Pharma

US Patent
LigandPNGBDBM387561(US10294212, No. 154 | N3-(3- Chloro-4- fluoropheny...)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His-tagged human recombinant IDO1 expressed in Escherichia coli using tryptophan as substrate by UV-visible absorption spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed