BDBM38821 6-Amino-4-(3-ethoxy-4-hydroxy-phenyl)-3-phenyl-1,4-dihydro-pyrano[2,3-c]pyrazole::6-amino-4-(3-ethoxy-4-hydroxy-phenyl)-3-phenyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::6-amino-4-(3-ethoxy-4-hydroxyphenyl)-3-phenyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::6-azanyl-4-(3-ethoxy-4-oxidanyl-phenyl)-3-phenyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::MLS000084991::SMR000019337::cid_3139811

SMILES CCOc1cc(ccc1O)C1C(C#N)C(=N)Oc2[nH]nc(c12)-c1ccccc1

InChI Key InChIKey=KXWNQHZFJRQRCS-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 38821   

TargetD(1A) dopamine receptor(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM38821(SMR000019337 | MLS000084991 | 6-Amino-4-(3-ethoxy-...)
Affinity DataEC50:  0.00738nMAssay Description:Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM38821(SMR000019337 | MLS000084991 | 6-Amino-4-(3-ethoxy-...)
Affinity DataEC50:  689nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM38821(SMR000019337 | MLS000084991 | 6-Amino-4-(3-ethoxy-...)
Affinity DataEC50:  6.40E+3nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetUbiquitin-conjugating enzyme E2 N(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM38821(SMR000019337 | MLS000084991 | 6-Amino-4-(3-ethoxy-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetM-phase inducer phosphatase 2(Human)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM38821(SMR000019337 | MLS000084991 | 6-Amino-4-(3-ethoxy-...)
Affinity DataIC50: 5.00E+4nMAssay Description:The Cdc25B Phosphatase HTS dose response confirmation has been developed to confirm actives identified in the Cdc25B HTS AID 368, screened at the Uni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetM17 leucyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM38821(SMR000019337 | MLS000084991 | 6-Amino-4-(3-ethoxy-...)
Affinity DataIC50: 7.71E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2011
Entry Details
PCBioAssay