BDBM388414 US10294246, Compound No. 111

SMILES CCO[C@@H](C(=O)N[C@@H](CC1COc2ccccc12)B(O)O)c1ccccc1

InChI Key InChIKey=AVNZVPLJVBSUQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 388414   

TargetProteasome subunit beta type-8(Human)
Merck Patent

US Patent
LigandPNGBDBM388414(US10294246, Compound No. 111)
Affinity DataIC50: 50nMAssay Description:Measurement of LMP7 inhibition is performed in 384 well format based on fluorescence intensity assay.Purified human immunoproteasome (0.25 nM) and se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
Merck Patent

US Patent
LigandPNGBDBM388414(US10294246, Compound No. 111)
Affinity DataIC50: 5.00E+3nMAssay Description:Measurement of Beta5 inhibition is performed in 384 well format based on fluorescence intensity assay.Purified human constitutive proteasome (1.25 nM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent