BDBM388738 (3R)-1-{2-Fluoro-4-[3-(1-quinolin-6-ylcyclopropyl)imidazo[1,2-a]pyrimidin-6-yl]benzyl}pyrrolidin-3-ol::US11261191, Example 68::US9944645, 68

SMILES O[C@@H]1CCN(Cc2ccc(cc2F)-c2cnc3ncc(n3c2)C2(CC2)c2ccc3ncccc3c2)C1

InChI Key InChIKey=XJHHVYGQGNFJKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 388738   

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandPNGBDBM388738(US9944645, 68 | (3R)-1-{2-Fluoro-4-[3-(1-quinolin-...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Incyte

US Patent
LigandPNGBDBM388738(US9944645, 68 | (3R)-1-{2-Fluoro-4-[3-(1-quinolin-...)
Affinity DataIC50: 500nMAssay Description:Compounds were screened in vitro for their ability to inhibit c-Met kinase activity. The IC50 values of compounds for the inhibition of c-Met kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent