BDBM388956 3-[9-[1-(4-amino-3-methyl- 1H-pyrazolo[3,4- d]pyrimidin-1-yl)ethyl]-7- chloro-6-fluoro-2-methyl- 2,3-dihydro-1,4- benzoxazepin-4(5H)- yl]azetidine-1-carboxamide::US9944646, Example 83

SMILES C[C@@H](c1cc(Cl)c(F)c2CN(CC(C)Oc12)C1CN(C1)C(N)=O)n1nc(C)c2c(N)ncnc12

InChI Key InChIKey=BAHZGSRWCFWACP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 388956   

LigandPNGBDBM388956(US9944646, Example 83 | 3-[9-[1-(4-amino-3-methyl-...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details
US Patent