BDBM38962 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione::6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione::6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine-2,4(1H,3H)-dione::6-[4-(3-chlorophenyl)piperazino]-3-cyclohexyl-uracil::MLS000094380::SMR000029966::cid_3238389

SMILES O=c1cc(N2CCN(c3cccc(Cl)c3)CC2)[nH]c(=O)n1C1CCCCC1

InChI Key InChIKey=CHMQQIFPOIZPIJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 38962   

TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 38962BDBM38962(MLS000094380 | 6-[4-(3-chlorophenyl)piperazin-1-yl...)
Affinity DataIC50: 315nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 38962BDBM38962(MLS000094380 | 6-[4-(3-chlorophenyl)piperazin-1-yl...)
Affinity DataIC50: 440nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 38962BDBM38962(MLS000094380 | 6-[4-(3-chlorophenyl)piperazin-1-yl...)
Affinity DataIC50: 675nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetIsoform 2 of Nuclear receptor ROR-alpha (Alpha-2)(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 38962BDBM38962(MLS000094380 | 6-[4-(3-chlorophenyl)piperazin-1-yl...)
Affinity DataIC50: 863nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetNuclear receptor subfamily 5 group A member 2(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 38962BDBM38962(MLS000094380 | 6-[4-(3-chlorophenyl)piperazin-1-yl...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of full length LRH1 transfected in HEK293T cells incubated for 20 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed