BDBM390705 (S)-4-(6-Amino-5,6,7,8-tetrahydronaphthalen-2-ylamino)benzonitrile::US9957261, Example 47

SMILES N[C@H]1CCc2cc(Nc3ccc(cc3)C#N)ccc2C1

InChI Key InChIKey=QLZWFEWQSVLZKH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390705   

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 390705BDBM390705(US9957261, Example 47 | (S)-4-(6-Amino-5,6,7,8-tet...)
Affinity DataKi:  50.5nMAssay Description:Mouse:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 390705BDBM390705(US9957261, Example 47 | (S)-4-(6-Amino-5,6,7,8-tet...)
Affinity DataKi:  116nMAssay Description:Rat:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent