BDBM390784 US9957263, Example 46

SMILES CC(C)c1ccc(cc1)S(=O)(=O)Nc1cccc(Oc2ccc(cc2-c2cn(C)c(=O)c3[nH]ccc23)S(C)(=O)=O)c1

InChI Key InChIKey=WMYQBJAXEYSGML-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 390784   

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390784(US9957263, Example 46)
Affinity DataKi:  1.80nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Abbvie

US Patent
LigandPNGBDBM390784(US9957263, Example 46)
Affinity DataKi:  10nMAssay Description:Compound dilution series were prepared in DMSO via a 3-fold serial dilution from 2.5 mM to 42 nM. Compounds were then diluted 6:100 in assay buffer (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent