BDBM391548 US10472358, Example 42B::US10781209, Example 42B::US11059821, Example 42::US11702416, Example 42::US12227502, Example 42B::US9957268, Example 42::US9957268, Example 42A::US9957268, Example 42B

SMILES COc1cc2c(c(-c3cn(C)c(=O)c4[nH]ncc34)c1)OC(C1CCCC1)C(=O)N2

InChI Key InChIKey=ZQNWOJLLSNTBOT-UHFFFAOYSA-N

Data  28 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 28 hits for monomerid = 391548   

TargetBromodomain-containing protein 4 [349-460](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/18/2023
Entry Details
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TargetBromodomain-containing protein 4 [44-167](Human)
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LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/18/2023
Entry Details
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TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhibitors were...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/17/2025
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
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US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhibitors were...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/17/2025
Entry Details
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TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhibitors were...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/17/2025
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhibitors were...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/17/2025
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhibitors were...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/17/2025
Entry Details
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TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhibitors were...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/17/2025
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/14/2020
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [42-168](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2020
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/14/2020
Entry Details
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TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2020
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [42-168](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2020
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [75-147](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/14/2020
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/14/2020
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2020
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [75-147](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/3/2021
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [42-168](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2020
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/3/2021
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2020
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [75-147](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/3/2021
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/3/2021
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [75-147](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/3/2021
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/3/2021
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [42-168](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/2/2022
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [342-460](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/2/2022
Entry Details
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TargetBromodomain-containing protein 4 [75-147](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/14/2020
Entry Details
Copy BDB DOIUS Patent

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TargetBromodomain-containing protein 4 [368-440](Human)
Incyte

US Patent

LigandBDBM391548(US9957268, Example 42 | US9957268, Example 42A | U...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/14/2020
Entry Details
Copy BDB DOIUS Patent

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