BDBM391741 US10300058, Compound 26::pyrimidin-4-yl)amino)phenyl)acrylamide

SMILES COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)C1CCN(CCF)CC1

InChI Key InChIKey=GWNADOKGQKZFAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391741   

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391741(US10300058, Compound 26 | pyrimidin-4-yl)amino)phe...)
Affinity DataIC50: 510nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391741(US10300058, Compound 26 | pyrimidin-4-yl)amino)phe...)
Affinity DataIC50: 2.50E+4nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent