BDBM391745 N-(3-((2-((2-acetyl-1,2,3,4-tetrahydroisoquinoline-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide ::US10300058, Compound 37

SMILES CC(=O)N1CCc2c(C1)cccc2Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F

InChI Key InChIKey=MSISUFHZEJVFKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391745   

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391745(US10300058, Compound 37 | N-(3-((2-((2-acetyl-1,2,...)
Affinity DataIC50: 9.90E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391745(US10300058, Compound 37 | N-(3-((2-((2-acetyl-1,2,...)
Affinity DataIC50: 1.28E+6nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent