BDBM391747 N-(3-((2-((2-methoxy-4-(3-(methylsulfonyl)propoxy)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide ::US10300058, Compound 43

SMILES COc1cc(OCCCS(C)(=O)=O)ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F

InChI Key InChIKey=KEYMOZJHSVZVMG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 391747   

TargetEpidermal growth factor receptor [T790M](Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391747(US10300058, Compound 43 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 3.60E+3nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Xuanzhu Pharma

US Patent
LigandPNGBDBM391747(US10300058, Compound 43 | N-(3-((2-((2-methoxy-4-(...)
Affinity DataIC50: 1.59E+5nMAssay Description:Test compounds: a part of compounds of the invention, the chemical names and preparation methods of which can be found in their preparation examples....More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
US Patent