BDBM393054 US10301323, Compound F18

SMILES Nc1ccccc1NC(=O)c1ccc(C=C2CN(Cc3cccnc3)C2)cc1

InChI Key InChIKey=MZFFLCMLPXTRKR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 393054   

TargetHistone deacetylase 1(Human)
Biomarin Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 393054BDBM393054(US10301323, Compound F18)
Affinity DataIC50: 1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
Biomarin Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 393054BDBM393054(US10301323, Compound F18)
Affinity DataIC50: 1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Biomarin Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 393054BDBM393054(US10301323, Compound F18)
Affinity DataIC50: 1.00E+3nMAssay Description:The HDAC activity inhibition assay was performed as follows to determine the ability of a test compound to inhibit HDAC enzymatic activity. Serial di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2020
Entry Details
US Patent