BDBM393399 3-((3'-Methoxy-[1,1'-biphenyl]-4-yl)(phenyl)methoxy)azetidine-1-carbonitrile::US9963444, Example 100
SMILES COc1cccc(c1)-c1ccc(cc1)C(OC1CN(C1)C#N)c1ccccc1
InChI Key InChIKey=SGFMJKFESZEQMF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 393399
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Northeastern University
Curated by ChEMBL
Northeastern University
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair