BDBM395275 N-4-[[(7R) or (7S)]-7-Methyl-4-oxo-3-(phenylamino)-1,4,5,6,7,8-hexahydrocyclohepta[b]pyrrol-2-yl]pyridin-2-ylacetamide::US10308629, Example 39

SMILES CC(=O)Nc1cc(-c2[nH]c3c(c2Nc2ccccc2)C(=O)CC[C@@H](C)C3)ccn1

InChI Key InChIKey=DCSLEQACTDXRET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395275   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 395275BDBM395275(US10308629, Example 39 | N-4-[[(7R) or (7S)]-7-Met...)
Affinity DataIC50: 5nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent