BDBM395968 US10308660, Example 45

SMILES Cn1c(nc(N)c(Sc2ccccc2Br)c1=O)N1CCC(C)(CN)CC1

InChI Key InChIKey=LDKYUDUNYFYLAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395968   

LigandPNGBDBM395968(US10308660, Example 45)
Affinity DataIC50: 137nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent