BDBM396570 3-(5-Bromo-2-phenethyloxy-phenoxy)-azetidine::US9981909, Example 195

SMILES Brc1ccc(OCCc2ccccc2)c(OC2CNC2)c1

InChI Key InChIKey=BZEQTUGEIYXVPQ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 396570   

Target5-hydroxytryptamine receptor 7(Rat)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396570(3-(5-Bromo-2-phenethyloxy-phenoxy)-azetidine | US9...)
Affinity DataKi:  2nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396570(3-(5-Bromo-2-phenethyloxy-phenoxy)-azetidine | US9...)
Affinity DataKi:  4nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396570(3-(5-Bromo-2-phenethyloxy-phenoxy)-azetidine | US9...)
Affinity DataKi:  10nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 6(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396570(3-(5-Bromo-2-phenethyloxy-phenoxy)-azetidine | US9...)
Affinity DataKi:  27nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396570(3-(5-Bromo-2-phenethyloxy-phenoxy)-azetidine | US9...)
Affinity DataKi:  42nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetSodium-dependent serotonin transporter(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396570(3-(5-Bromo-2-phenethyloxy-phenoxy)-azetidine | US9...)
Affinity DataKi:  60nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent