BDBM396924 US9981963, Compound 15

SMILES CC(C)(O)Cn1cc(-c2cn[nH]c2)c2cc(ncc12)C#CC(C)(O)c1nccs1

InChI Key InChIKey=GKBUYXSYXLTAMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396924   

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396924(US9981963, Compound 15)
Affinity DataIC50: 10nMAssay Description:Assay buffer was 50 mM Tris pH 7.5 containing 1 mM EGTA (ethylene glycol tetraacetic acid), 1 mM DTT (dithiothreitol), 0.1 mM Na3VO4, 5 mM MgCl2, 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2020
Entry Details
US Patent