BDBM398047 US10322118, Entry 5

SMILES c1cc(c(cc1Oc2c(cc(cc2I)C[C@@H](C(=O)O)N)I)I)O

InChI Key InChIKey=AUYYCJSJGJYCDS-UHFFFAOYSA-N

Data  2 IC50

PDB links: 14 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 398047   

TargetThyroid hormone receptor beta(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM398047(US10322118, Entry 5)
Affinity DataIC50: 0.103nMAssay Description:Agonist activity at GAL4 DNA-binding domain fused TRbeta receptor (unknown origin) ligand binding domain expressed in UAS-bla HEK 293T cells assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPutative hydrolase(Pseudomonas aeruginosa (strain UCBPP-PA14))
Dartmouth College

US Patent
LigandPNGBDBM398047(US10322118, Entry 5)
Affinity DataIC50: 2.10E+4nMAssay Description:The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent