BDBM398048 US10322118, Entry 6

SMILES c1c(cc(c(c1I)Oc2cc(c(c(c2)I)O)I)I)C[C@@H](C(=O)O)N

InChI Key InChIKey=XUIIKFGFIJCVMT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 26 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 398048   

TargetMacrophage migration inhibitory factor(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM398048(US10322118, Entry 6)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of recombinant human MIF expressed in Escherichia coli BL21(DE3) using L-dopa as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPutative hydrolase(Pseudomonas aeruginosa (strain UCBPP-PA14))
Dartmouth College

US Patent
LigandPNGBDBM398048(US10322118, Entry 6)
Affinity DataIC50: 1.00E+5nMAssay Description:The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2020
Entry Details
US Patent