BDBM399981 US10323042, Example 60::US10738063, Example 60

SMILES Cc1cncc(c1)-c1c2OCCCn2nc1C(=O)N1CCC1

InChI Key InChIKey=QSAFHZCASRDUOV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 399981   

LigandPNGBDBM399981(US10323042, Example 60 | US10738063, Example 60)
Affinity DataIC50: 2.89E+4nMAssay Description:Human PDE4B1 coding sequence (amino acids 122 to 736 from the sequence with accession number Q07343) with the mutations resulting in the amino acid s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandPNGBDBM399981(US10323042, Example 60 | US10738063, Example 60)
Affinity DataIC50: 2.89E+4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent

LigandPNGBDBM399981(US10323042, Example 60 | US10738063, Example 60)
Affinity DataIC50: 3.00E+4nMAssay Description:A portion of the human PDE4D3 coding sequence (amino acids 50 to 672 from the sequence with accession number Q08499-2) was cloned into the baculoviru...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandPNGBDBM399981(US10323042, Example 60 | US10738063, Example 60)
Affinity DataIC50: 3.00E+4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
US Patent