BDBM40478 2-[(4-methoxyphenyl)methylsulfanyl]-6-methyl-1H-pyrimidin-4-one::2-[(4-methoxyphenyl)methylthio]-6-methyl-1H-pyrimidin-4-one::6-methyl-2-(p-anisylthio)-1H-pyrimidin-4-one::CHEMBL500351::MLS000109390::SMR000105333::cid_716696

SMILES COc1ccc(CSc2nc(C)cc(=O)[nH]2)cc1

InChI Key InChIKey=XMFWHLZTTUUQHL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 40478   

TargetCollagenase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM40478(MLS000109390 | SMR000105333 | cid_716696 | 2-[(4-m...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant MMP13 by fluorogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM40478(MLS000109390 | SMR000105333 | cid_716696 | 2-[(4-m...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human recombinant MMP13 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM40478(MLS000109390 | SMR000105333 | cid_716696 | 2-[(4-m...)
Affinity DataIC50: 4.32E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2011
Entry Details
PCBioAssay
TargetCollagenase 3(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM40478(MLS000109390 | SMR000105333 | cid_716696 | 2-[(4-m...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant MMP13 by HxBPyne probe-based competitive activity based protein profiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM40478(MLS000109390 | SMR000105333 | cid_716696 | 2-[(4-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP8 by fluorogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM40478(MLS000109390 | SMR000105333 | cid_716696 | 2-[(4-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MMP9 by fluorogenic substrate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed