BDBM405567 US10351547, Compound 1-15::US10597377, Compound 1-15

SMILES Cc1cc(F)cc(c1)-c1ccc2nnc(-c3cc(F)cc(c3)C(N)=O)c(N3CCC(N)CC3)c2c1

InChI Key InChIKey=YCXIGIIQWRCOCC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 405567   

TargetSomatostatin receptor type 2(Human)
Crinetics Pharmaceuticals

US Patent
LigandPNGBDBM405567(US10351547, Compound 1-15 | US10597377, Compound 1...)
Affinity DataEC50:  55nMAssay Description:Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC #CCL-61) stably expressing the human SSTR2 are plated in each well of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details
US Patent

TargetSomatostatin receptor type 2(Human)
Crinetics Pharmaceuticals

US Patent
LigandPNGBDBM405567(US10351547, Compound 1-15 | US10597377, Compound 1...)
Affinity DataEC50:  55nMAssay Description:Four days prior to the assay, 5,000 Chinese hamster ovary cells (CHO-K1, ATCC # CCL-61) stably expressing the human SSTR2 are plated in each well of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent