BDBM410045 1-(3-(4-(tert-Butyl)-1H-imidazol-1-yl)cyclobutyl)-3-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)imidazolidin-2-one::US10370352, Example 5

SMILES CC(C)n1cnnc1-c1cccc(n1)N1CCN(C2CC(C2)n2cnc(c2)C(C)(C)C)C1=O

InChI Key InChIKey=BVZGAXKBDAGYIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410045   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Eli Lilly

US Patent
LigandPNGBDBM410045(1-(3-(4-(tert-Butyl)-1H-imidazol-1-yl)cyclobutyl)-...)
Affinity DataIC50: 1.84nMAssay Description:The assay is done using an ADP-Glo Kinase Assay Kit (Promega, Catalog #V9102) according to the manufacturer's protocol with the following modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent