BDBM410048 1-(6-(4-Isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-3-(3-(2-methylpyrimidin-5-yl)cyclobutyl)imidazolidin-2-one, isomer 2::US10370352, Example 9

SMILES CC(C)n1cnnc1-c1cccc(n1)N1CCN(C2CC(C2)c2cnc(C)nc2)C1=O

InChI Key InChIKey=BBHOJLYASOAJHM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 410048   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Eli Lilly

US Patent
LigandPNGBDBM410048(1-(6-(4-Isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-...)
Affinity DataIC50: 6.21nMAssay Description:The assay is done using an ADP-Glo Kinase Assay Kit (Promega, Catalog #V9102) according to the manufacturer's protocol with the following modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent