BDBM415698 US10442759, Compound I-10

SMILES OC(=O)CN(c1ccc(OC(C(O)=O)c2ccccc2)c2ccccc12)S(=O)(=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=RTPITAGATRSMQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 415698   

TargetNuclear factor erythroid 2-related factor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM415698(US10442759, Compound I-10)
Affinity DataIC50: 6.66E+3nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM415698(US10442759, Compound I-10)
Affinity DataIC50: 6.66E+3nMAssay Description:The instrument used in the FP experiment was the SpectraMax Multi-Mode Microplate Reader (Molecular Devices), and the excitation and emission wavelen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent