BDBM41576 US8614220, A45B2C1Z

SMILES NC(=O)c1nn(CCF)c-2c1CCc1cnc(Nc3ccccc3OC(F)(F)F)nc-21

InChI Key InChIKey=ZPROSCYPYBVWCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 41576   

TargetSerine/threonine-protein kinase PLK1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM41576(US8614220, A45B2C1Z)
Affinity DataIC50: 26nMpH: 3.0Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
US Patent