BDBM415924 1-(5-chloro-6-(2H- 1,2,3-triazol-2- yl)pyridin-3-yl)-3-(2- chloro-7-((S)-1-(((S)- tetrahydrofuran-3- yl)oxy)ethyl)pyrazolo [1,5-a]pyrimidin-6- yl)urea::US10442808, Example 101
SMILES C[C@H](O[C@H]1CCOC1)c1c(NC(=O)Nc2cnc(c(Cl)c2)-n2nccn2)cnc2cc(Cl)nn12
InChI Key InChIKey=RTCANLSNLOZYHV-AAEUAGOBSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 415924
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1 [329-824](Human)
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 0.00500nMAssay Description:The assay employs a short peptide substrate labeled with the single fluorophore PT14 as a fluorescence lifetime probe sensitive to the cleavage state...More data for this Ligand-Target Pair