BDBM41649 2-[[1-(4-chlorophenyl)-1,2,3,4-tetrazol-5-yl]sulfanylmethyl]-5,7-dimethyl-imidazo[1,2-a]pyrimidine::2-[[1-(4-chlorophenyl)tetrazol-5-yl]sulfanylmethyl]-5,7-dimethylimidazo[1,2-a]pyrimidine::2-[[[1-(4-chlorophenyl)-5-tetrazolyl]thio]methyl]-5,7-dimethylimidazo[1,2-a]pyrimidine::2-[[[1-(4-chlorophenyl)tetrazol-5-yl]thio]methyl]-5,7-dimethyl-imidazo[1,2-a]pyrimidine::MLS000048449::SMR000062208::cid_2999642

SMILES Cc1nc2c(s1)c(=O)n(-c1ccc(C[C@H](NC(=O)c3c(C)cc(N4CCOC[C@@H]4C(F)(F)F)cc3F)C(=O)O)c3cccnc13)c(=O)n2C

InChI Key InChIKey=RKQHDFLTZSAQMT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 41649   

TargetIntegrin alpha-4/beta-7(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 41649BDBM41649(US11116760, Example 410)
Affinity DataEC50:  0.0540nMAssay Description:The CHO cell line was cultured in T-175 flasks at 37 degrees C and 95% relative humidity (RH). The growth media consisted of Dulbecco's Modified ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent