BDBM417368 US10457654, Example 227
SMILES CN(C)[C@H]1C[C@H](CC[C@@H]1Nc1cc(F)c(cc1Br)S(=O)(=O)Nc1ccncn1)c1cccc(c1)C(F)(F)F
InChI Key InChIKey=XZIIYADHVARGOG-BUKVSMQUSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 417368
Affinity DataIC50: 1.19nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Affinity DataIC50: 0.690nMAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Following the procedure described in Example 243A, and making modificati...More data for this Ligand-Target Pair