BDBM417562 6-[5-chloro-2-({8- oxabicyclo[3.2.1]octan- 3-yl}amino)pyrimidin- 4-yl]-2-[2-oxo-2-(1,2,3,4- tetrahydroisoquinolin- 2-yl)ethyl]-2,3-dihydro- 1H-isoindol-1-one::US10457669, Example 177::US11001575, Example 177

SMILES Clc1cnc(NC2CC3CCC(C2)O3)nc1-c1ccc2CN(CC(=O)N3CCc4ccccc4C3)C(=O)c2c1

InChI Key InChIKey=KYOQSIQQAUGHQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 417562   

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM417562(6-[5-chloro-2-({8- oxabicyclo[3.2.1]octan- 3-yl}am...)
Affinity DataIC50: 82nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM417562(6-[5-chloro-2-({8- oxabicyclo[3.2.1]octan- 3-yl}am...)
Affinity DataIC50: 82nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2021
Entry Details
US Patent