BDBM4180 1,6-naphthyridin-2(1H)-one deriv. 7m::3-(2,6-Dichlorophenyl)-7-[[3-(imidazol-1-yl)propyl]amino]-1-methyl-1,6-naphthyridin-2(1H)-one::3-(2,6-dichlorophenyl)-7-{[3-(1H-imidazol-1-yl)propyl]amino}-1-methyl-1,2-dihydro-1,6-naphthyridin-2-one

SMILES Cn1c2cc(NCCCn3ccnc3)ncc2cc(-c2c(Cl)cccc2Cl)c1=O

InChI Key InChIKey=BSMKGOSXJLCJOB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4180   

TargetFibroblast growth factor receptor 1(Human)
University of Auckland

LigandPNGBDBM4180(3-(2,6-Dichlorophenyl)-7-[[3-(imidazol-1-yl)propyl...)
Affinity DataIC50: 210nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Auckland

LigandPNGBDBM4180(3-(2,6-Dichlorophenyl)-7-[[3-(imidazol-1-yl)propyl...)
Affinity DataIC50: 540nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Auckland

LigandPNGBDBM4180(3-(2,6-Dichlorophenyl)-7-[[3-(imidazol-1-yl)propyl...)
Affinity DataIC50: 3.20E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2005
Entry Details Article
PubMed