BDBM418609 N-methyl-4-({4-[({2- [methyl(methylsulfonyl)amino]pyridin- 3-yl}methyl)amino]-5- (trifluoromethyl)pyrimidin-2- yl}amino)benzamide (53)::US10450297, Example 53
SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3cccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1
InChI Key InChIKey=FKCIIMYQSRTZNM-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 418609
Affinity DataIC50: 0.590nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human pyk2More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human FAKMore data for this Ligand-Target Pair