BDBM418853 N-[3-({[2-({4-[(1R)-1- aminoethyl]phenyl}amino)-5- (trifluoromethyl)pyrimidin-4- yl]amino}methyl)phenyl]-N- methylmethanesulfonamide (353), hydrochloride salt::US10450297, Example 353

SMILES C[C@@H](N)c1ccc(Nc2ncc(c(NCc3cccc(c3)N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1

InChI Key InChIKey=MMGJCPGSNNEILZ-CQSZACIVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418853   

TargetFocal adhesion kinase 1 [410-689](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM418853(N-[3-({[2-({4-[(1R)-1- aminoethyl]phenyl}amino)-5-...)
Affinity DataIC50: <0.595nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent