BDBM418868 3-fluoro-N-methyl-4-({4-[({3- [methyl(methylsulfonyl)amino]pyrazin-2- yl}methyl)amino]-5- (trifluoromethyl)pyrimidin-2- yl}amino)benzamide (368)::US10450297, Example 368::US10450297, Example 369

SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)c(F)c1

InChI Key InChIKey=ZMSSFJVOTAQPMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 418868   

TargetFocal adhesion kinase 1 [410-689](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM418868(3-fluoro-N-methyl-4-({4-[({3- [methyl(methylsulfon...)
Affinity DataIC50:  1.49nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFocal adhesion kinase 1 [410-689](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM418868(3-fluoro-N-methyl-4-({4-[({3- [methyl(methylsulfon...)
Affinity DataIC50: <0.595nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent