BDBM419691 US10464919, Example 29

SMILES Cc1cc(CN2CCN(c3ccc(C#N)c(F)c3)CC2)cc2[nH]c(=O)c3c(c12)NCCC3

InChI Key InChIKey=QPUPKVDVCFODAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 419691   

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 419691BDBM419691(US10464919, Example 29)
Affinity DataIC50: 24.7nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent