BDBM419706 US10464919, Example 44

SMILES Cc1cc(C#N)ccc1N1CCN(Cc2cc(CO)c3c4c(c(=O)[nH]c3c2)CCCN4)CC1

InChI Key InChIKey=PIGMESWGBPFZJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 419706   

TargetPoly [ADP-ribose] polymerase 1(Human)
Je Il Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 419706BDBM419706(US10464919, Example 44)
Affinity DataIC50: 11.6nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent